The symptoms of osteomyelitis can vary depending on the type and duration of the infection. Common signs and symptoms include:

1. Pain: Persistent, deep, and throbbing pain in the affected bone, often worsening with movement.

2. Fever: A high temperature, which may indicate the presence of infection.

3. Swelling: Swelling, redness, and warmth around the affected area.

4. Limited Mobility: Difficulty moving the affected limb or joint due to pain and swelling.

5. Fatigue: Feeling tired and unwell, especially in cases of chronic osteomyelitis.

6. Drainage: Pus or other fluids may drain from an open wound or sinus tract connected to the infected bone.